Overweight and obesity are very common
diseases around the globe, and prevalence continues
to increase in most countries. In Bulgaria about 58 %  of
the population above 18 years of age is either overweight
or obese, and this proportion is still increasing. The below presented Table 1 and Table 2  demonstrate the increase in the proportion of obesity in
Bulgaria during recent years.
Table 1 Overweight and obesity prevalence in schoolchildren (National survey on nutrition and nutritional status of schoolchildren in Bulgaria (-1998, 2010-2011 )
Table 2 Prevalence of Overweight and Obesity among adults (19 – 60 years old) National Monitoring of Dietary Intake and Nutritional Status, 1998, 2004
Bee products are a milestone for the health Balkan
nutrition. Our studies stress on the important role of the
apidietics (nutritional regiment, enriched with propolis,
honey, royal jelly, bee polen, laclarville etc.) in the
prevention on treatment of obesity and atherogenic risk
factors (V.Vasilve and E. Petkov, 200, 2004; Sv. Handjiev
et al., 1995-2001). On the base of these studies we created
a series of dietary products [3, 4] for treatment and
prevention of obesity and metabolic syndrome – Biocorect+,
containing a mixture of propolis, multiflavour honey, bee
polen and various herbs and bioactive substances. Our
hypothesis is that the products Biocorect+ have an effect
on the stomach mucosa, respectively on the secretion of
the stomach hormones ghrelin and obestatin. Thus, there is
a positive effect on the metabolic process.
The aim of our study is to describe food
supplements designed for prevention and treatment of
obesity and related disorders. It concerns six different
food supplements containing bee products, different herbs
and many biologically active substances. These foods are
designed for persons, who not only suffer from overweight,
but also from arterial hypertension, dyslipidemia, arthrosis
and those in psycho-emotional stresses.
Materials and Methods
The following supplements from the line Biocorect
have been studied:
• Biocorect universal – for overweight people without
essential complications. Helps to decrease the over
increased appetite. Increases organism’s bioenergetics.
Leads to a feeling of satiety. The purgative effect is
moderate and well accepted by the organism. Helps total
strengthening of the organism. It has powerful antioxidant
effects and a good interaction with all medicine, food and
• Biocorect without propolis and bee-honey, and with
extra. GarciniaCambogia – garcinia is an Asiatic fruit
and its extract is a concentrate of hydroxicitric acid.
According to competent researches it has been shown to
decrease excessive appetite, improve food absorption /
so that the organism would satisfy itself with less food/,
and has thermogenic effect / accelerates excessive calorie
burning by more than 10%/. Antraquinon glycosides in
PhamnusFrangula L and Senna act to loosen and eliminate
the self-poisoning in the organism, which initiates
some obese forms as well as other diseases. Softening
components of mallow and linseed calm irritated mucous
membranes of digestive organs and together with previous
components help normalize peristalsis and metabolism.
Corn hair is a tested mean for kidney cleansing and
liberation of hold liquids accumulated in kidneys, tissues
and intercellular spaces /with or without oedemas/.
Thanks to the complexity of well-studied biologically
active components /valepotriats, organic acid, etc/, the
Valerianae eliminates stress-induced tension, which
makes many people overeat when it is needless for their
body. Concentrated extracts from natural products contain
valuable vitamins, minerals, and antioxidants, which
supplement and strengthenthe organism.
• Biocorect-high blood pressure- for overweight people
with high blood pressure. Affects the cardiovascular
system favorably. Calms down the over-stimulation.
Helps to normalize body weight and blood pressure. Has
moderate purgative and diuretic action.
• Biocorect-high cholesterol – for overweight people
with high total cholesterol, high low density /the bad one/
cholesterol, and increased triglycerides. It strengthens the
organism’s bioenergetics. It affects favorably body weight
values, total, HDL and LDL cholesterol and triglycerides.
Has an antioxidant effect. Decreases early arterial sclerosis
and cardiovascular diseases risk.
• Biocorect-joint problems – for overweight people with
joint problems /”exostoses“ and different degenerative
joint changes/. Increases organism’s bioenergetics. Has
an antioxidant and analgesic effect. Helps decrease
overweight and concomitant joint complaints. Helps
strengthen the organism generally. Has good interactions
with all medicine, food and diet regimes.
• Biocorect-gall-stone Gallic troubles –for overweight
people with gallstone gallic troubles/gravel and gallstones in gallbladder and bile-duct,gallic dyskinesia/.
Helps to decrease overweigh and stimulates gastric, gallic
and pancreatic secretions. Has analgesic and anti-spasm
effect. Increases the feeling of satiation.
• Biocorect-nervous tension – for overweight people with
psycho emotional distress. Helps to decrease body weight
and strengthens the nervous system generally. Calms
down the over stimulation and helps regulate the sleep.
Decreases the increased appetite.
The food supplements mentioned above have been
tested among 302 individuals diagnosed with obesity (171
– females and 131 – males). The mean age was 46.3 years
and mean body mass index (BMI) 32.8 kg/M2. After allergy
examination the food /Biocorect universal/ was prescribed
as follows: 5 days – 3x40 drops 15 minutes before eating;
2 days- 2x60 drops /at 10a.m. and at 4p.m. in a cup of tea/.
At the beginning and at the end of the first and second
month’s anthropometric indexes – height, weight, BMI,
waist circumference, fat mass, lean body mass, lean body
mass/lean mass ratio, visceral body fat – were examined.
The anthropometric measurements are completed with
impedance apparatus “Tanita 420”. Sagittal diameter was
also measured using a caliper. From the markers of the
lipid exchange is tested – total cholesterol (mmol/l), LDLcholesterol (mmol/l) and triglycerides (mmol/l). All tests
were made at the beginning and in the end of the research.
We have also tested systolic blood pressure (SBP) and
diastolic blood pressure (DBP). The results are statistically
processed and for a statistical significance is considered
*** BMI – Body Mass Index; FM – Fat Mass, LBM - Lean Body Mass; VBM – Visceral Body Mass; W – Waist; H – Hips; SG – Sagittal Diameter
After two months a significant reduction of mean
weight and waist circumference was observed (Table 1)
– weight by 9 kg, waist circumference by 13 cm, p<0.01.
FM decreases by 4.2 % and LBM increases by 4.2% and
resp. the ration LBM/FM increases. All these results
emphasize the favorable effect of the tested supplement on
body composition of the patients. It should also be taken
into account that the decrease of the VBM, W, the ration
W/H and SD shows a lowered risk for cardiovascular
Figure 1. Weight changes in kilograms over the course of the study.
Figure 2. Body Mass Index (BMI) changes over the course of the study
Figure 3. Waist changes (cm) over the course of the study.
Figure 4. Fat Mass (%) during the study.
Figure 5. Lean Body Mass (LBM)/ Fat Mass (FM) ratio changes over the course of the study.
Table 4. Lipid status and blood pressure was also ameliorated for this period.
At the end of the treatment there was a detected
improvement in psychological status.
The decrease of the visceral fat mass corresponds
to the decrease of the sagital diameter and all this data
shows the decrease of cardiovascular complications and
also the decrease of the atherogenic risk factors.
In obese persons, Biocorect exhibits a favorable effect and
is well tolerable for the patients.
1. Our results demonstrate that food supplements Biocorect
exhibit a healing effect in obese persons.
2. Biocorect has the capacity to reduce the body weight
(resp. BMI), FM, VBM, W, SD, hyperlipidemias, high
blood pressure and atherogenesis.
3. The product does not present side effects in the patients.